Identification of Saccharomyces cerevisiae GLY1 as a threonine aldolase: a key enzyme in glycine biosynthesis.

doi:10.1111/j.1574-6968.1997.tb10349.x

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Article

Identification of Saccharomyces cerevisiae GLY1 as a threonine aldolase: a key enzyme in glycine biosynthesis.

FEMS microbiology letters - 1 May 1997

Monschau N, Stahmann K P, Sahm H, McNeil J B, Bognar A L

Abstract excerpt

Determination of enzyme-specific activities revealed that GLY1 encodes a threonine aldolase (TA) in Saccharomyces cerevisiae. A knock-out mutant auxotrophic for glycine lacked detectable activity. After transformation with YEp24GLY1 glycine prototrophy was restored and TA-specific activity was 16...

Topics

Alanine Transaminase
Aldehyde-Lyases
Ethanol
Fungal Proteins
Glucose
Glycine
Glycine Hydroxymethyltransferase
Kinetics
Models, Chemical
Mutation
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins
Transaminases

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