13C NMR analysis of intercompartmental flow of one-carbon units into choline and purines in Saccharomyces cerevisiae.

doi:10.1021/bi00167a010

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Article

13C NMR analysis of intercompartmental flow of one-carbon units into choline and purines in Saccharomyces cerevisiae.

Biochemistry - 11 Jan 1994

Pasternack L B, Laude D A, Appling D R

Abstract excerpt

In Saccharomyces cerevisiae, the three-carbon of serine is normally the major one-carbon donor, although glycine and formate can substitute for serine. The second carbon of glycine enters via the glycine cleavage system in the mitochondria and can satisfy all cellular one-carbon requirements. It...

Topics

Adenine
Carbon Isotopes
Choline
Formates
Genotype
Glycine
Guanine
Magnetic Resonance Spectroscopy
Models, Biological
Purines
Saccharomyces cerevisiae
Serine

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