Article
Mutation scanning of the p53 tumor suppressor gene in renal and liver transplant patients in Hungary.
Transplantation proceedings - 1 Mar 2005
Sarvary E, Nagy P, Benjamin A, Szoke M, Remport A, Jansen J, Nemes B, Kobori L, Fehervari I, Sulyok B, Perner F, Varga M, Fazakas J, Lakatos M, Szabo M, Toth A, Járay J
Abstract excerpt
INTRODUCTION: The increased incidence of malignancies among transplanted patients is well known. Abnormal function of the p53 tumor suppressor gene has been reported in more than half of all tumors. The aim of our study was to detect point mutations of p53 gene in transplanted patients because the presence of mutations may be a predictive factor for tumor development. An earlier diagnosis can help to develop new...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.