Article
Caspase-3 can be pseudo-activated by a Ca2+-dependent proteolysis at a non-canonical site.
FEBS letters - 25 Apr 2005
Pelletier Maude, Oliver Lisa, Meflah Khaled, Vallette François M
Abstract excerpt
We have shown previously that calcium could trigger nuclear fragmentation, which was associated with a caspase 3 (C3)-like activity [Juin, P., Pelletier, M., Oliver, L., Tremblais, K., Gregoire, M., Meflah, K. and Vallette, F.M. (1998) Induction of a caspase-3-like activity by calcium in normal cytosolic extracts triggers nuclear apoptosis in a cell-free system. J. Biol. Chem. 273, 17559]. Here, we report that...
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