Article
Genomic and gene expression signature of the pre-invasive testicular carcinoma in situ.
Cell and tissue research - 1 Oct 2005
Almstrup Kristian, Ottesen Anne Marie, Sonne Si Brask, Hoei-Hansen Christina E, Leffers Henrik, Rajpert-De Meyts Ewa, Skakkebaek Niels E
Abstract excerpt
Testicular cancer is the most common malignancy among men in the reproductive age and the incidence is increasing, probably caused by environmental factors. Most testicular cancers are testicular germ cell tumours and all originate from a carcinoma in situ (CIS) pattern. In this review, we focus on the pre-invasive CIS and its possible fetal origin by reviewing recent data originating from DNA microarrays and...
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