Article
Screening for inhibitors of microtubule-associated motor proteins.
Methods in molecular medicine - 1 Jan 2007
Kozielski Frank, DeBonis Salvatore, Skoufias Dimitrios A
Abstract excerpt
The mitotic spindle is an important target for cancer chemotherapy. The main protein target for drugs in clinical use is tubulin, the building block of microtubules. In recent years, other proteins of the mitotic spindle have been identified as potential targets for the development of more specif...
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