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Article

Higher-order molecular packing in amyloid-like fibrils constructed with linear arrangements of hydrophobic and hydrogen-bonding side-chains.

Journal of molecular biology - 13 May 2005

Saiki Masatoshi, Honda Shinya, Kawasaki Kazunori, Zhou Deshan, Kaito Akira, Konakahara Takeo, Morii Hisayuki

Abstract excerpt

Various mutants of the protein fragment, barnase module-1 (1-24) were investigated in order to reveal the structural principle of amyloid-like fibrils. By means of circular dichroism spectroscopy, X-ray diffraction, electron microscopy, and thioflavin T binding assay, we found that the molecules containing two beta-strands and an intervening turn structure are assembled to form a cross-beta structure....

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Identifiers

PMID: 15843028
DOI: 10.1016/j.jmb.2005.03.022

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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