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Article

The importance of steric zipper on the aggregation of the MVGGVV peptide derived from the amyloid beta peptide.

Journal of biomolecular structure & dynamics - 1 Aug 2010

Chang Liang-Kai, Zhao Jian-Hua, Liu Hsuan-Liang, Wu Josephine W, Chuang Chih-Kuang, Liu Kung-Tien, Chen Jenn-Tzong, Tsai Wei-Bor, Ho Yih

Abstract excerpt

Amyloid-like fibrils are found in many fatal diseases, such as Alzheimer's disease, Parkinson's disease, type II diabetes mellitus, and prion diseases. Recently, the structural characterization of the MVGGVV peptide from the C-terminal hydrophobic segment of the amyloid-B (AB) peptide has revealed a general feature of amyloid-like fibrils, termed as "steric zipper", which is constituted by a tight side-chain...

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Identifiers

PMID: 20476794
DOI: 10.1080/07391102.2010.10507342

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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