Article
Insight into the stability of cross-beta amyloid fibril from molecular dynamics simulation.
Biopolymers - 1 Jun 2010
Chen Yue, He Yong-Jie, Wu Maoying, Yan Guanwen, Li Yixue, Zhang Jian, Chen Hai-Feng
Abstract excerpt
Amyloid fibrils are considered to play causal roles in the pathogenesis of amyloid-related degenerative diseases such as Alzheimer's disease, type II diabetes mellitus, the transmissible spongiform encephalopathies, and prion disease. The mechanism of fibril formation is still hotly debated and r...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
