Article
Polymorphisms of the interleukin-18 gene in periodontitis patients.
Journal of clinical periodontology - 1 May 2005
Folwaczny Matthias, Glas Jürgen, Török Helga-Paula, Tonenchi Laurian, Paschos Ekaterini, Bauer Bernhard, Limbersky Olga, Folwaczny Christian
Abstract excerpt
BACKGROUND: Interleukin (IL)-18 regulates the expression of the proinflammatory cytokine interferon (IFN)-gamma. The present study sought to test the putative involvement of six different IL-18 gene polymorphisms in pre-disposition to destructive periodontal disease. METHODS: A total of 123 patie...
Topics
- Adult
- Aged
- Alleles
- Case-Control Studies
- Chi-Square Distribution
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Interleukin-18
- Male
- Middle Aged
- Periodontitis
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Polymorphism, Single Nucleotide
