Article
Polymorphisms of the interleukin-18 gene in periodontitis patients.
Journal of clinical periodontology - 1 May 2005
Folwaczny Matthias, Glas Jürgen, Török Helga-Paula, Tonenchi Laurian, Paschos Ekaterini, Bauer Bernhard, Limbersky Olga, Folwaczny Christian
Abstract excerpt
BACKGROUND: Interleukin (IL)-18 regulates the expression of the proinflammatory cytokine interferon (IFN)-gamma. The present study sought to test the putative involvement of six different IL-18 gene polymorphisms in pre-disposition to destructive periodontal disease. METHODS: A total of 123 patients with periodontitis and 121 healthy controls were genotyped for six IL-18 polymorphisms at position -656, -607,...
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