Article
Analysis of tumor necrosis factor-alpha, transforming growth factor-beta, interleukin-10, IL-6, and interferon-gamma gene polymorphisms in patients with chronic periodontitis.
Journal of periodontology - 1 Dec 2006
Babel Nina, Cherepnev Georgy, Babel Daniel, Tropmann Alla, Hammer Markus, Volk Hans-Dieter, Reinke Petra
Abstract excerpt
BACKGROUND: Cytokine gene polymorphisms may have an impact on the susceptibility to and progression of chronic periodontitis. In this study, we analyzed the -1082 interleukin-10 (IL-10), -308 tumor necrosis factor-alpha (TNF-alpha), transforming growth factor-beta 1 (TGF-beta1) (codons 10 and 25)...
Topics
- Adult
- Aged
- Case-Control Studies
- Chronic Disease
- Female
- Genetic Predisposition to Disease
- Humans
- Interferon-gamma
- Interleukin-10
- Interleukin-6
- Male
- Middle Aged
- Periodontitis
- Polymorphism, Single Nucleotide
- Reference Values