Article
Association of Polymorphism in IL-18 Gene with Periodontitis in Uyghur Adults in Xinjiang and Evidence from Six Case-Control Studies with a Comprehensive Analysis.
Immunological investigations - 1 Apr 2022
Shan Chao, Ma Ting, Wang Ting Ting, Wu Long, Abasijiang Aisaiti, Zhao Jin
Abstract excerpt
AIM: The aim of the study was to evaluate the association of IL-18 137 G > C, 607 C > A gene polymorphism in Uyghur population with chronic periodontitis (CP) and combine the results with the meta-analysis. METHODS: In a case-control study, 200 cases with CP and 100 healthy controls were recruited; IL-18 137 G > C, 607 C > A genotyping was performed by polymerase chain reaction-restriction fragment length...
Topics
- Adult
- Case-Control Studies
- China
- Chronic Periodontitis
- Genetic Predisposition to Disease
- Humans
- Interleukin-18
- Polymorphism, Single Nucleotide