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Article

TLR4 and IL-18 gene variants in aggressive periodontitis.

Journal of clinical periodontology - 1 Dec 2008

Noack Barbara, Görgens Heike, Lorenz Katrin, Ziegler Andreas, Hoffmann Thomas, Schackert Hans Konrad

Abstract excerpt

AIM: We aimed to assess the association of different genotypes with increased aggressive periodontitis susceptibility by studying functional relevant variants in the pathogen-recognition receptor Toll-like receptor 4 (TLR4) and variants in the promoter region of the pro-inflammatory cytokine interleukin-18 (IL-18). MATERIAL AND METHODS: One hundred and eleven patients with aggressive periodontitis and 80...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18983635
DOI: 10.1111/j.1600-051X.2008.01334.x

Genes

TLR4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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