Article
Interleukin-10 (-592 C/A) and interleukin-12B (+16974 A/C) gene polymorphisms and the interleukin-10 ATA haplotype are associated with periodontitis in a Taiwanese population.
Journal of periodontal research - 1 Jun 2009
Hu K-F, Huang K-C, Ho Y-P, Lin Y-C, Ho K-Y, Wu Y-M, Yang Y-H, Tsai C-C
Abstract excerpt
BACKGROUND AND OBJECTIVE: Single nucleotide polymorphisms are assumed to be associated with the differential production of cytokines. We evaluated gene polymorphisms of interleukin-10 (-592C>A, -819C>T and -1082G>A) and interleukin-12B (+16974) in patients with chronic periodontitis (n = 145) and...
Topics
- Adult
- Aggressive Periodontitis
- Asian People
- Case-Control Studies
- Chronic Periodontitis
- Female
- Gene Frequency
- Genetic Predisposition to Disease
- Haplotypes
- Humans
- Interleukin-10
- Interleukin-12 Subunit p40
- Logistic Models
- Male
- Middle Aged