Article
Structural changes in exon 11 of MEF2A are not related to sporadic coronary artery disease in Han Chinese population.
European journal of clinical investigation - 1 Aug 2010
Dai Da-Peng, Zhou Xiao-Yang, Xiao Yao, Xu Feng, Sun Fu-Cheng, Ji Fu-Sui, Zhang Zhi-Xin, Hu Ji-Hong, Guo Jian, Zheng Jun-De, Dong Jia-Mei, Zhu Wei-Guo, Shen Yan, Qian Yi-Jian, He Qing, Cai Jian-Ping
Abstract excerpt
BACKGROUND: A mutation in MEF2A (myocyte enhancer factor-2A) had been reported to be the first gene linked directly to coronary artery disease (CAD). However, an opposing opinion was proposed recently that MEF2A mutations are not a common cause of sporadic CAD. In this study, we screened exon 11 of the MEF2A gene in people of the Han nationality in China and finished some functional analysis of found variations....
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