Article
Effect of lac repressor oligomerization on regulatory outcome.
Molecular microbiology - 1 Apr 1992
Chakerian A E, Matthews K S
Abstract excerpt
Regulatory outcome in a bacterial operon depends on the interactions of all the components which influence mRNA production. Levels of mRNA can be altered profoundly by both negative and positive regulatory elements which modulate initiation of transcription. The occupancy of regulatory sites on the DNA by repressors and activators is determined not only by the affinity of these proteins for their cognate site(s)...
Topics
- DNA, Bacterial
- Escherichia coli
- Gene Expression Regulation, Bacterial
- Lac Operon
- Mutation
- Polymers
- Repressor Proteins