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Article

Frequent Overexpression of <i>STK15/Aurora-A/BTAK</i> and Chromosomal Instability in Tumorigenic Cell Cultures Derived From Human Ovarian Cancer

1 Jan 2005

Abstract excerpt

The STK15 (also known as Aurora-A/BTAK) gene localized on chromosome 20q13 and encoding a centrosome-associated serine/threonine kinase is amplified and overexpressed in multiple human tumor cell types. Overexpression of this gene is involved in tumorigenic transformation, induction of centrosome duplication-distribution abnormalities, and aneuploidy in mammalian cells. To examine the potential role of STK15 in...

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PMID: 15839305
DOI: 10.3727/096504005775082101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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