Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Overexpression and amplification of STK15 in human gliomas

1 Dec 2004

Abstract excerpt

The serine/threonine kinase 15 (STK15) at chromosome 20q13.2 is frequently shown to be amplified and overexpressed in several human cancers. STK15 has been reported to act as a cell cycle regulator and its overexpression induces centrosome amplification and aneuploidy. Recently we showed that STK15 even plays a role in human malignant brain tumours and we described an amplification of the gene in 31% of the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to RNA Research and Splicing
Share to Genomics and Chromatin Dynamics
Share to Glioma Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 15547718
DOI: 10.3892/ijo.25.6.1789

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Overexpression and amplification of STK15 in human gliomasPMID 15547718Read ↗

Amplification/Overexpression of a Mitotic Kinase Gene in Human Bladder CancerSemantic proximity Read ↗

STK15 gene overexpression, centrosomal amplification, and chromosomal instability in the absence of STK15 mutations in laryngeal carcinoma.Semantic proximity Read ↗

Microarray-based screening for molecular markers in medulloblastoma revealed STK15 as independent predictor for survival.Semantic proximity Read ↗

Frequent Overexpression of <i>STK15/Aurora-A/BTAK</i> and Chromosomal Instability in Tumorigenic Cell Cultures Derived From Human Ovarian CancerSemantic proximity Read ↗

Aurora-A/STK15/BTAK enhances chromosomal instability in bladder cancer cellsSemantic proximity Read ↗

Upregulation of STK15 in esophageal squamous cell carcinomas in a Mongolian population.Semantic proximity Read ↗

Association of centrosomal kinaseSTK15/BTAK mRNA expression with chromosomal instability in human breast cancersSemantic proximity Read ↗

KUB3 amplification and overexpression in human gliomas.Semantic proximity Read ↗

Identification of Stk6/STK15 as a candidate low-penetrance tumor-susceptibility gene in mouse and human.Semantic proximity Read ↗

[Study on STK15 gene abnormality and centrosomal amplification in laryngeal carcinoma].Semantic proximity Read ↗

Synergistic effects of STK15 gene polymorphisms and endogenous estrogen exposure in the risk of breast cancer.Semantic proximity Read ↗

Functional STK15 Phe31Ile polymorphism is associated with the occurrence and advanced disease status of esophageal squamous cell carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.