Article
Overexpression and amplification of Aurora-A in hepatocellular carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Mar 2004
Jeng Yung-Ming, Peng Shian-Yang, Lin Chiao-Ying, Hsu Hey-Chi
Abstract excerpt
PURPOSE: Aurora-A/STK15/BTAK, a centrosome-associated serine/threonine kinase, has been shown to induce chromosomal instability, leading to aneuploidy and cell transformation. The purpose of this study was to investigate the expression and amplification of Aurora-A in hepatocellular carcinoma (HC...
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