Defining Sepsis Phenotypes-Two Murine Models of Sepsis and Machine Learning.

Abstract excerpt

INTRODUCTION: The immunobiology defining the clinically apparent differences in response to sepsis remains unclear. We hypothesize that in murine models of sepsis we can identify phenotypes of sepsis using non-invasive physiologic parameters (NIPP) early after infection to distinguish between different inflammatory states. METHODS: Two murine models of sepsis were used: gram-negative pneumonia (PNA) and cecal...

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