Article
MMP-9 microsatellite polymorphism and susceptibility to exudative form of age-related macular degeneration.
Genetics in medicine : official journal of the American College of Medical Genetics - 1 Apr 2005
Fiotti Nicola, Pedio Marcella, Battaglia Parodi Maurizio, Altamura Nicola, Uxa Laura, Guarnieri Gianfranco, Giansante Carlo, Ravalico Giuseppe
Abstract excerpt
PURPOSE: To assess if a polymorphism (PM) of the microsatellite (CA(13-27)) in the promoter region of Matrix Metalloproteinase 9 (MMP-9) was associated with the exudative form of age-related macular degeneration (AMD) and to its risk factors. METHODS: In 107 patients with AMD (AMD Group) and 223 age- and gender-matched controls (Control Group) with cataract, demographic, clinical data, and MMP-9 PM have been...
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