Article
The association of matrix metalloproteinases polymorphisms and interleukins in advanced age-related macular degeneration.
Ophthalmic genetics - 1 Aug 2018
Budiene Brigita, Liutkeviciene Rasa, Gustiene Olivija, Ugenskiene Rasa, Laukaitiene Danguole, Savukaityte Aiste, Vilkeviciute Alvita, Steponaviciute Rasa, Rocyte Aurelija, Zaliuniene Dalia
Abstract excerpt
PURPOSE: To assess the impact of matrix metalloproteinase (MMP)1-1607 1G/2G (rs1799750), MMP7-181 A/G (rs11568818) single-nucleotide polymorphism and systemic cytokins interleukin-1 beta (IL-1β), IL-6 levels on the development of exudative age-related macular degeneration (eAMD) Methodology: The study group comprised 282 patients with eAMD, and the control group enrolled 379 randomly selected persons. The...
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