Article
The genetic variant rs4073 A→T of the Interleukin-8 promoter region is associated with the earlier onset of exudative age-related macular degeneration.
Acta ophthalmologica - 1 Dec 2015
Hautamäki Asta, Seitsonen Sanna, Holopainen Juha M, Moilanen Jukka A, Kivioja Jarno, Onkamo Päivi, Järvelä Irma, Immonen Ilkka
Abstract excerpt
PURPOSE: To study the association of the single nucleotide polymorphism (SNP) rs4073 in the interleukin-8 (IL-8) promoter region with the diagnosis and age of onset of exudative age-related macular degeneration (AMD) in association with the known genetic risk factors for AMD and tobacco smoking. METHODS: Medical records, smoking history and angiograms or fundus photographs of 301 patients with exudative AMD, 72...
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