Article
Interleukin 8 promoter polymorphism predicts the initial response to bevacizumab treatment for exudative age-related macular degeneration.
Retina (Philadelphia, Pa.) - 1 Oct 2013
Hautamäki Asta, Kivioja Jarno, Vavuli Satu, Kakko Sakari, Savolainen Eeva-Riitta, Savolainen Markku J, Liinamaa M Johanna, Seitsonen Sanna, Onkamo Päivi, Järvelä Irma, Immonen Ilkka
Abstract excerpt
PURPOSE: To study the association of single-nucleotide polymorphisms of interleukin 8, vascular endothelial growth factor, erythropoietin, complement factor H, complement component C3, and LOC387715 genes with the response to bevacizumab treatment in exudative age-related macular degeneration. METHODS: Clinical records, smoking history, optical coherence tomography, and angiographies of 96 bevacizumab-treated...
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