Article
Association of exudative age-related macular degeneration with matrix metalloproteinases-2 (-1306 C/T) rs243865 gene polymorphism.
Indian journal of ophthalmology - 1 Apr 2018
Liutkeviciene Rasa, Vilkeviciute Alvita, Borisovaite Dominyka, Miniauskiene Goda
Abstract excerpt
Purpose: Age-related macular degeneration (AMD) is a disease of the macula that significantly affects eyesight and leads to irreversible central vision loss. Recent studies have demonstrated that angiogenesis is the most important mechanism of AMD development. It is associated with extracellular remodeling involving different proteolytic systems, among them matrix metalloproteinases (MMPs), which play an...
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