Article
Integrin-linked kinase mediates bone morphogenetic protein 7-dependent renal epithelial cell morphogenesis.
Molecular and cellular biology - 1 May 2005
Leung-Hagesteijn Chungyee, Hu Ming Chang, Mahendra Ahalya S, Hartwig Sunny, Klamut Henry J, Rosenblum Norman D, Hannigan Gregory E
Abstract excerpt
Bone morphogenetic protein 7 (BMP7) stimulates renal branching morphogenesis via p38 mitogen-activated protein kinase (p38(MAPK)) and activating transcription factor 2 (ATF-2) (M. C. Hu, D. Wasserman, S. Hartwig, and N. D. Rosenblum, J. Biol. Chem. 279:12051-12059, 2004). Here, we demonstrate a novel role for integrin-linked kinase (ILK) in mediating renal epithelial cell morphogenesis in embryonic kidney...
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