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Article

Dopamine transporter genotype and methylphenidate dose response in children with ADHD.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Jul 2005

Stein Mark A, Waldman Irwin D, Sarampote Christopher S, Seymour Karen E, Robb Adelaide S, Conlon Charles, Kim Soo-Jeong, Cook Edwin H

Abstract excerpt

Stimulant medications, such as methylphenidate (MPH), are the most commonly used, effective treatment for ADHD. MPH acts primarily by inhibiting the dopamine transporter (DAT), a protein responsible for the reuptake of dopamine from the synapse into presynaptic terminals. We sought to evaluate the relationship between DAT1 3'-untranslated region (3'-UTR) variable number tandem repeats (VNTR) genotypes and dose...

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Identifiers

PMID: 15827573
DOI: 10.1038/sj.npp.1300718

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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