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Article

Pharmacogenetic predictors of methylphenidate dose-response in attention-deficit/hyperactivity disorder.

Journal of the American Academy of Child and Adolescent Psychiatry - 1 Nov 2011

Froehlich Tanya E, Epstein Jeffery N, Nick Todd G, Melguizo Castro Maria S, Stein Mark A, Brinkman William B, Graham Amanda J, Langberg Joshua M, Kahn Robert S

Abstract excerpt

OBJECTIVE: Because of significant individual variability in attention-deficit/hyperactivity disorder (ADHD) medication response, there is increasing interest in identifying genetic predictors of treatment effects. This study examined the role of four catecholamine-related candidate genes in moderating methylphenidate (MPH) dose-response. METHOD: Eighty-nine stimulant-naive children with ADHD 7 to 11 years old...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 22024001
DOI: 10.1016/j.jaac.2011.08.002
PMCID: PMC3225067

Genes

DRD4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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