Article
Dopamine transporter genotype and stimulant dose-response in youth with attention-deficit/hyperactivity disorder.
Journal of child and adolescent psychopharmacology - 1 Jun 2014
Stein Mark A, Waldman Irwin, Newcorn Jeffrey, Bishop Jeffrey, Kittles Rick, Cook Edwin H
Abstract excerpt
OBJECTIVES: This study seeks to determine if variation in the dopamine transporter gene (SLC6A3/DAT1) moderates the dose-response effects of long-acting dexmethylphenidate (D-MPH) and mixed amphetamine salts (MAS) in children with attention-deficit/hyperactivity disorder (ADHD). METHODS: Fifty-six children and adolescents (mean age=11.7±2.2) participated in a double-blind, two period crossover, dose-response...
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