Article
Neurocognitive effects of methylphenidate on ADHD children with different DAT genotypes: a longitudinal open label trial.
European journal of paediatric neurology : EJPN : official journal of the European Paediatric Neurology Society - 1 Jul 2013
Pasini A, Sinibaldi L, Paloscia C, Douzgou S, Pitzianti M B, Romeo E, Curatolo P, Pizzuti A
Abstract excerpt
The variable number of tandem repeat polymorphism in the 3'-untranslated region of the dopamine transporter gene (DAT) may influence the variability of the therapeutic response to methylphenidate (MPH) in Attention Deficit/Hyperactivity Disorder (ADHD). For this reason we evaluated the neuropsychological functioning after a prolonged period of MPH treatment and after a specific time from MPH suspension....
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