Article
'PACLIMS': a component LIM system for high-throughput functional genomic analysis.
BMC bioinformatics - 12 Apr 2005
Donofrio Nicole, Rajagopalon Ravi, Brown Douglas, Diener Stephen, Windham Donald, Nolin Shelly, Floyd Anna, Mitchell Thomas, Galadima Natalia, Tucker Sara, Orbach Marc J, Patel Gayatri, Farman Mark, Pampanwar Vishal, Soderlund Cari, Lee Yong-Hwan, Dean Ralph A
Abstract excerpt
BACKGROUND: Recent advances in sequencing techniques leading to cost reduction have resulted in the generation of a growing number of sequenced eukaryotic genomes. Computational tools greatly assist in defining open reading frames and assigning tentative annotations. However, gene functions cannot be asserted without biological support through, among other things, mutational analysis. In taking a genome-wide...
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