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Article

Allele effects in MHC-peptide interactions: a theoretical analysis of HLA-DRbeta10101-HA and HLA-DRbeta10401-HA complexes.

Biochemical and biophysical research communications - 20 May 2005

Cárdenas Constanza, Ortiz Marysol, Balbín Alejandro, Villaveces José Luis, Patarroyo Manuel E

Abstract excerpt

HLA-DRbeta1*0101-HA and HLA-DRbeta1*0401-HA complexes are studied and compared by means of their computationally derived multipolar moments and electrostatic potentials. Changes in electrostatic potential are associated with definite pocket interaction profiles. Thus, Pocket 1 projects itself as an anchoring pocket for both complexes, in accordance with experimental results. While Pocket 4 has an anchoring...

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Identifiers

PMID: 15823565
DOI: 10.1016/j.bbrc.2005.03.102

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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