Article
Nitric oxide: a major determinant of mast cell phenotype and function.
Memorias do Instituto Oswaldo Cruz - 1 Mar 2005
McCauley S D, Gilchrist M, Befus A D
Abstract excerpt
Mast cells (MC) are important in the numerous physiological processes of homeostasis and disease. Most notably, MC are critical effectors in the development and exacerbation of allergic disorders. Nitric oxide (NO) is a diatomic radical produced by nitric oxide synthase (NOS), and has pluripotent cell signaling and cytotoxic properties. NO can influence many MC functions. Recent evidence shows the source of this...
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