Article
Diverse phenotypes of outward currents in cells that have survived in the 5-day-infarcted heart.
American journal of physiology. Heart and circulatory physiology - 1 Aug 2005
Dun Wen, Boyden Penelope A
Abstract excerpt
We have shown reduced density and altered kinetics in slowly activating K+ currents (I(Ks)) in epicardial border zone (EBZ) cells (IZs) of the 5-day-infarcted canine heart (Jiang M, Cabo, C, Yao J-A, Boyden PA, and Tseng G-N. Cardiovasc Res 48: 34-43, 2000). beta-Adrenergic stimulation with isoproterenol increases I(Ks) in normal cells (NZs). In this study, we used a voltage-clamp protocol with an external...
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