Article
Inward rectifier potassium channels in the HL-1 cardiomyocyte-derived cell line.
Journal of cellular physiology - 1 Nov 2010
Goldoni Dana, Zhao YouYou, Green Brian D, McDermott Barbara J, Collins Anthony
Abstract excerpt
HL-1 is a line of immortalized cells of cardiomyocyte origin that are a useful complement to native cardiomyocytes in studies of cardiac gene regulation. Several types of ion channel have been identified in these cells, but not the physiologically important inward rectifier K(+) channels. Our aim was to identify and characterize inward rectifier K(+) channels in HL-1 cells. External Ba(2+) (100 µM) inhibited...
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