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Article

Phenotypic differences in transient outward K+ current of human and canine ventricular myocytes: insights into molecular composition of ventricular Ito.

American journal of physiology. Heart and circulatory physiology - 1 Feb 2004

Akar Fadi G, Wu Richard C, Deschenes Isabelle, Armoundas Antonis A, Piacentino Valentino, Houser Steven R, Tomaselli Gordon F

Abstract excerpt

The Ca(2+)-independent transient outward K(+) current (I(to)) plays an important electrophysiological role in normal and diseased hearts. However, its contribution to ventricular repolarization remains controversial because of differences in its phenotypic expression and function across species....

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Source

Identifiers

PMID: 14527940
DOI: 10.1152/ajpheart.00673.2003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-14527940-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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