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Article

Introduction of extended LEC14-type branching into core-fucosylated biantennary N-glycan.

The FEBS journal - 1 Apr 2005

André Sabine, Kojima Shuji, Prahl Ingo, Lensch Martin, Unverzagt Carlo, Gabius Hans-Joachim

Abstract excerpt

A series of enzymatic substitutions modifies the basic structure of complex-type biantennary N-glycans. Among them, a beta1,2-linked N-acetylglucosamine residue is introduced to the central mannose moiety of the core-fucosylated oligosaccharide by N-acetylglucosaminyltransferase VII. This so-called LEC14 epitope can undergo galactosylation at the beta1,2-linked N-acetylglucosamine residue. Guided by the...

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PMID: 15819890
DOI: 10.1111/j.1742-4658.2005.04637.x

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