Article
Complex N-glycans are the major ligands for galectin-1, -3, and -8 on Chinese hamster ovary cells.
Glycobiology - 1 Apr 2006
Patnaik Santosh Kumar, Potvin Barry, Carlsson Susanne, Sturm David, Leffler Hakon, Stanley Pamela
Abstract excerpt
Galectins are implicated in a large variety of biological functions, many of which depend on their carbohydrate-binding ability. Fifteen members of the family have been identified in vertebrates based on binding to galactose (Gal) that is mediated by one or two, evolutionarily conserved, carbohydrate-recognition domains (CRDs). Variations in glycan structures expressed on glycoconjugates at the cell surface may,...
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