Article
A family-based association study of schizophrenia with polymorphisms at three candidate genes.
Neuroscience letters - 29 Apr 2005
Duan Shiwei, Gao Rui, Xing Qinghe, Du Jing, Liu Zhuangjun, Chen Qi, Wang Hongsheng, Feng Guoyin, He Lin
Abstract excerpt
Clinical researches have shown that there is a genetic contribution to the pathogenesis of schizophrenia. Recent studies have suggested that three genes neuropeptide Y (NPY), phosphoinositide-3-kinase class 3 (PIK3C3) and 14-3-3 eta chain gene (YWHAH) are probably associated with schizophrenia. To replicate these findings, we carried out a family-based study on a sample of 235 trios. Our results suggest that the...
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