Article
Family-based association of YWHAH in psychotic bipolar disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Oct 2009
Grover Deepak, Verma Ranjana, Goes Fernando S, Mahon Pamela L Belmonte, Gershon Elliot S, McMahon Francis J, Potash James B, Gershon Elliot S, McMahon Francis J, Potash James B
Abstract excerpt
YWHAH is a positional and functional candidate gene for both schizophrenia and bipolar disorder (BP). This gene has been previously shown to be associated with both disorders, and the chromosome location (22q12.3) has been repeatedly implicated in linkage studies for these disorders. It codes for the eta subtype of the 14-3-3 protein family, is expressed mainly in brain, and is involved in HPA axis regulation. We...
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