Article
ANK3 as a risk gene for schizophrenia: new data in Han Chinese and meta analysis.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Dec 2012
Yuan Aihua, Yi Zhenghui, Wang Qiang, Sun Jinhua, Li Zhiqiang, Du Yasong, Zhang Chen, Yu Tao, Fan Juan, Li Huafang, Yu Shunying
Abstract excerpt
Histological and neuroimaging evidence supports the hypothesis that neuronal disconnectivity may be involved in the pathogenesis of schizophrenia. A genome-wide association study (GWAS) showed a single nucleotide polymorphism (SNP), rs10761482 in ankyrin 3 (ANK3), a major neuron-enriched gene, was associated with schizophrenia although inconsistent results had been reported. Two meta analyses reported another SNP...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.