Article
Comparative functional study of the viral telomerase RNA based on natural mutations.
The Journal of biological chemistry - 24 Jun 2005
Fragnet Laetitia, Kut Emmanuel, Rasschaert Denis
Abstract excerpt
Telomerase activity is present in most malignant tumors and provides a mechanism for the unlimited potential for division of neoplastic cells. We previously characterized the first identified viral telomerase RNA (vTR) encoded by the Marek's disease virus (MDV) (Fragnet, L., Blasco, M. A., Klapper, W., and Rasschaert, D. (2003) J. Virol. 77, 5985-5996). This avian herpesvirus induces T-lymphomas. We demonstrated...
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