Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alternative splicing and nonsense-mediated decay regulate telomerase reverse transcriptase (TERT) expression during virus-induced lymphomagenesis in vivo.

BMC cancer - 21 Oct 2010

Amor Souheila, Remy Sylvie, Dambrine Ginette, Le Vern Yves, Rasschaert Denis, Laurent Sylvie

Abstract excerpt

BACKGROUND: Telomerase activation, a critical step in cell immortalization and oncogenesis, is partly regulated by alternative splicing. In this study, we aimed to use the Marek's disease virus (MDV) T-cell lymphoma model to evaluate TERT regulation by splicing during lymphomagenesis in vivo, from the start point to tumor establishment. RESULTS: We first screened cDNA libraries from the chicken MDV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Chickens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Flow Cytometry

Share to Gene Expression Regulation, Enzymologic

Share to Gene Library

Share to Lymphoma

Share to Telomerase

Share to Up-Regulation

Source

Open in PubMed Open full text

Identifiers

PMID: 20964812
DOI: 10.1186/1471-2407-10-571
PMCID: PMC2976754

Genes

TERT
UPF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alternative splicing and nonsense-mediated decay regulate telomerase reverse transcriptase (TERT) expression during virus-induced lymphomagenesis in vivo.PMID 20964812Read ↗

Complicated RNA splicing of chicken telomerase reverse transcriptase revealed by profiling cells both positive and negative for telomerase activity.Semantic proximity Read ↗

TERT accelerates BRAF mutant–induced thyroid cancer dedifferentiation and progression by regulating ribosome biogenesisSemantic proximity Read ↗

A virus-encoded telomerase RNA promotes malignant T cell lymphomagenesis.Semantic proximity Read ↗

Alternatively spliced telomerase reverse transcriptase variants lacking telomerase activity stimulate cell proliferation.Semantic proximity Read ↗

Alternative Splicing of Human Telomerase Reverse Transcriptase (hTERT) and Its Implications in Physiological and Pathological ProcessesSemantic proximity Read ↗

TERT accelerates BRAF mutant-induced thyroid cancer dedifferentiation and progression by regulating ribosome biogenesisSemantic proximity Read ↗

Exploration of Alternative Splicing (AS) Events in MDV-Infected Chicken Spleens.Semantic proximity Read ↗

Alternative Splicing of hTERT Pre-mRNA: A Potential Strategy for the Regulation of Telomerase Activity.Semantic proximity Read ↗

Herpesvirus telomerase RNA(vTR)-dependent lymphoma formation does not require interaction of vTR with telomerase reverse transcriptase (TERT).Semantic proximity Read ↗

Telomerase flies the coop: the telomerase RNA component as a viral-encoded oncogene.Semantic proximity Read ↗

The RNA Subunit of Telomerase Is Encoded by Marek's Disease VirusSemantic proximity Read ↗

Exclusion of Exon 2 Is a Common mRNA Splice Variant of Primate Telomerase Reverse TranscriptasesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.