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Article

Molecular mechanism underlying the thermal stability and pH-induced unfolding of CHABII.

Journal of molecular biology - 22 Apr 2005

Wei Zheng, Song Jianxing

Abstract excerpt

The 37-residue alpha/beta protein CHABII was previously demonstrated to undergo a gradual pH-induced unfolding. It has been shown that even at pH 4.0 CHABII still retained a highly native-like secondary structure and tertiary topology although its tight side-chain packing was severely disrupted, typical of the molten globule state. Here, we have expressed and refolded the recombinant proteins of CHABII and its...

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Identifiers

PMID: 15808864
DOI: 10.1016/j.jmb.2005.02.028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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