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Article

Structure of the acid state of Escherichia coli ribonuclease HI.

Biochemistry - 17 Sept 1996

Dabora J M, Pelton J G, Marqusee S

Abstract excerpt

Under acidic conditions Escherichia coli ribonuclease HI* (RNase H*) adopts a partially folded state with all of the properties of a molten globule. Using amide hydrogen exchange carried out under acid state conditions, followed by quenching and NMR detection on the native state, we have determined the residues that are responsible for the observed structure of the acid state. Although RNase H* is a mixed alpha +...

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Identifiers

PMID: 8810899
DOI: 10.1021/bi9611671

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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