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Article

Versatility of non-native forms of human cytochrome c: pH and micellar concentration dependence.

Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry - 1 Jan 2013

Simon Matthieu, Metzinger-Le Meuth Valérie, Chevance Soizic, Delalande Olivier, Bondon Arnaud

Abstract excerpt

In addition to its electron transfer activity, cytochrome c is now known to trigger apoptosis via peroxidase activity. This new function is related to a structural modification of the cytochrome upon association with anionic lipids, particularly cardiolipin present in the mitochondrial membrane. However, the exact nature of the non-native state induced by this interaction remains an active subject of debate. In...

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PMID: 23070294
DOI: 10.1007/s00775-012-0946-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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