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Article

p53 deficiency does not affect mutation rate in the mouse germline.

Oncogene - 16 Jun 2005

Burr Karen L-A, Smith Andrew G, Dubrova Yuri E

Abstract excerpt

Although the influence of p53 deficiency on somatic genetic stability is well established, its effect in the germline is poorly understood. Mutation rates at two expanded simple tandem repeat (ESTR) loci were studied in the germline of nonexposed and irradiated p53-deficient mice. Spontaneous mutation rates in the homozygous and heterozygous p53-deficient males did not significantly differ from that in the...

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Identifiers

PMID: 15806156
DOI: 10.1038/sj.onc.1208604

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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