Article
The effects of in utero irradiation on mutation induction and transgenerational instability in mice.
Mutation research - 12 May 2009
Barber Ruth C, Hardwick Robert J, Shanks Morag E, Glen Colin D, Mughal Safeer K, Voutounou Mariel, Dubrova Yuri E
Abstract excerpt
Epidemiological evidence suggests that the deleterious effects of prenatal irradiation can manifest during childhood, resulting in an increased risk of leukaemia and solid cancers after birth. However, the mechanisms underlying the long-term effects of foetal irradiation remain poorly understood. This study was designed to analyse the impact of in utero irradiation on mutation rates at expanded simple tandem...
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