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Article

Clinical relevance of Mycobacterium tuberculosis plcD gene mutations.

American journal of respiratory and critical care medicine - 15 Jun 2005

Yang Zhenhua, Yang Dong, Kong Ying, Zhang Lixin, Marrs Carl F, Foxman Betsy, Bates Joseph H, Wilson Frank, Cave M Donald

Abstract excerpt

To identify Mycobacterium tuberculosis virulence factors, we integrated comparative genomics and epidemiologic data analysis to investigate the relationship between certain genomic insertions and deletions in the phospholipase-C gene D (plcD) with the clinical presentation of tuberculosis (TB). Four hundred ninety-six well-characterized M. tuberculosis clinical isolates were studied. Approximately 30% (147) of...

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Identifiers

PMID: 15805187
DOI: 10.1164/rccm.200408-1147OC
PMCID: PMC2718484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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