Article
Distribution of insertion- and deletion-associated genetic polymorphisms among four Mycobacterium tuberculosis phospholipase C genes and associations with extrathoracic tuberculosis: a population-based study.
Journal of clinical microbiology - 1 Dec 2005
Kong Y, Cave M D, Yang D, Zhang L, Marrs C F, Foxman B, Bates J H, Wilson F, Mukasa L N, Yang Z H
Abstract excerpt
The Mycobacterium tuberculosis genome contains four phospholipase C (PLC)-encoding genes, designated plcA, plcB, plcC, and plcD, respectively. Each of the four genes contributes to the overall PLC activity of M. tuberculosis. PLC is hypothesized to contribute to M. tuberculosis virulence. Infecti...
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